Judith Faye Rubinson
Assistant Professor 

Department of Chemistry 
Georgetown University
37th and O Streets NW
Washington, DC 20057-1227

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Analytical Chemistry, Chemical Instrumentation, Advanced Topics in Analytical Chemistry

Analytical and Biomedical Applications of Conducting Polymers. The use of conducting polymers electrodes has expanded over the last few years to include a number of different areas. The long-term objectives of this line of research are the development of various types of electrodes modified with conducting polymers for use as electrochemical detectors or sensors and tailoring of these polymer electrodes for use in probing biochemical redox processes. Two different lines of research in our laboratory fall into this general area. the first is in the area of in vivo detection of neurotransmitters. We are currently developing methods for the reproducible production of conducting polymer fiber electrodes with diameters on the order of a micron for use in single cell sensing and condcuting polymer polymer modified noble metal electrodes for use in implanted sensors. Second, although great strides have been made in the fabrication of cardiac pacing and sensing leads, biocompatibility remains a problem. Strategies to address this problem center in our laboratory in the testing of various conducting polymer electrodes for use in these applications. t present focus on making the electrode smaller or incorporation of steroids into a modifying layer on the surface of the electrodes.

Polymeric Stationary Phases for Chromatography. Dibenzotetraazaannulene (DBTAA) macrocycles are under investigation for the development of stationary phases for separations and microextraction. These materials hold promise for differential binding of metal ions and also are under investigation for binding or microextraction of various amines, alcohols, and polycyclic aromatic compounds. There is particular interest in chiral derivatives of these for chiral separation.

H.B. Mark, Jr., H. Zhang, S.K. Lunsford, O. Ceylan, A. Khaskelis, S. Hausner, J.F. Rubinson, G.C. Russell, H. Zimmer, and G.P. Kreishman, "Synergistic Effects in the FIA determination of Catechol in the Presence of Excess Ascorbic Acid by Series Dual Band Amperometric Detection," Analytica Chimica Acta (1999) 385, 281.

J.F. Rubinson, “Biology to Engineering: The Present Status of Conducting Polymers,” in J.F. Rubinson and H.B. Mark, Jr., Conducting Polymers and Polymer Electrolytes: From Biology to Photovoltaics, (ACS symposium series #832), New York: Oxford University Press, 2003.

Marc Ovadia, Daniel H. Zavitz, Judith F. Rubinson, DaeGyun Park, Howard A. Chou, "Investigation of a semiconductor bioelectrode with ohmic behavior In Vivo: Impedance spectroscopy of p-type semiconductor electrodes in perfused living heart,", Chemical Physics Letters, 419 (2005) 277-287.